Phenylketonuria. Mass screening of newborns in Ireland.
نویسندگان
چکیده
منابع مشابه
Mass Screening of Newborns in Ireland
Phenylketonuria was, until recently, regarded as a very rare disease with an estimated incidence of between 1 in 18,000 and 1 in 40,000 (Centerwall, Berry, and Woolf, 1963). The results of massscreening surveys of newborns in the United States showed that the incidence was approximately 1 in 10,000 (MacCready and Hussey, 1964), while a similar experience in Israel showed an incidence of 1 in 90...
متن کاملPhenylketonuria: a reassessment of mass infant screening by napkin test.
Most local health authorities in Great Britain have used the Phenistix test on wet napkins or diapers (napkin-Phenistix test) to screen all young infants for phenylketonuria (Centerwall et al., 1963). This test is a sensitive and reliable method of detecting phenylpyruvic aciduria (Gibbs and Woolf, 1959; Woolf, 1963), which is an early sign of true phenylketonuria (Allen et al., 1964; Berry and...
متن کاملResults of routine screening for phenylketonuria in early infancy, Northern Ireland (1960-67).
The routine screening of newborns for phenylketonuria (PKU) was started in Northern Ireland during the early part of 1960. The method used initially was the Phenistix/napkin test, i.e. a Phenistix strip (Ames Labs.), was pressed between the folds of a wet napkin. Tests were carried out by Health Visitors on infants aged between 3 and 6 weeks. Because this screening procedure was not adopted by ...
متن کاملNorthern Ireland ( 1960 - 67 ) . phenylketonuria in early infancy , Results of routine screening for
The routine screening of newborns for phenylketonuria (PKU) was started in Northern Ireland during the early part of 1960. The method used initially was the Phenistix/napkin test, i.e. a Phenistix strip (Ames Labs.), was pressed between the folds of a wet napkin. Tests were carried out by Health Visitors on infants aged between 3 and 6 weeks. Because this screening procedure was not adopted by ...
متن کاملScreening for biopterin defects in newborns with phenylketonuria and other hyperphenylalaninemias.
The newborn screening for phenylketonuria (PKU) has become a common practice in many countries. The success of this type of mass screening is the result of the reliability of the Guthrie test in the identification of high blood phenylalanine levels. Recently, new syndromes other than PKU have been recognized that give high blood phenylalanine levels. These syndromes are referred to as “atypical...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1968
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.43.228.141